AbstractWe study (i.e., Dib et al. 2006) the virial balance of clumps and cores (CCs) in a set of three-dimensional numerical simulations of driven, magnetohydrodynamical, isothermal molecular clouds (MCs). The simulations represent a range of magnetic field strengths in MCs from subcritical to non-magnetic regimes. We developed a clump-finding algorithm to identify CCs at different threshold levels in the simulation box, and for each object, we calculate all the terms that enter the virial theorem in its Eulerian form. We also calculate, other quantities commonly used to indicate the state of gravitational boundedness of CCs such as the Jeans number J_c, the mass-to magnetic flux ratio μ_c, and the virial parameter α_vir. Our results suggest that a) CCs are dynamical out-of-equilibrium structures. b) The surface energies are of the same order than their volume counterparts and thus are very important in determining the exact energy balance in CCs. c) CCs can be either in the process of being compressed by the velocity field or of being dispersed. Yet, not all CCs that have a compressive velocity field at their boundaries are necessarily gravitationally bound. d) There is no one-to-one correspondence between the state of gravitational boundedness of a CC as described by the energy balance analysis (i.e., gravity versus other energies) or as implied by the classical indicators J_c, μ_c, and α_vir. In general, from the energy analysis, we observe that only the inner regions of the objects (i.e., the dense cores selected at high threshold levels) are gravitationally bound, whereas J_c and α_vir estimates tend to show that they are more gravitationally bound at the lowest threshold levels. g) We observe, in the non-magnetic simulation, the existence of a bound core with structural and dynamical properties that resemble those of the Bok globule Barnard 68 (B68). This suggests that B68 like cores can form in a larger molecular cloud and then be confined by the warm gas of a newly formed HII region, which can heat and rarefy the gas around the core, confine it, and extend its lifetime.