AbstractStar-formation regions in nearby galaxies provide an excellent laboratory to study star formation processes, evolution of massive stars and the properties of the surrounding interstellar medium. A wealth of information can be obtained from their spectral analysis of the emission lines and the stellar continuum. Considering these, we proposed a long-term project “Spectroscopic Observations of the Star Formation Regions in Nearby Galaxies”. The primary goal of this project is to observe spectroscopy of star formation regions in 20 nearby galaxies, with the NAOC 2.16 m telescope and the Hectospec/MMT multifiber spectrograph. With the spectra of a large sample of star formation regions, combining multi-wavelength data from UV to IR, we can investigate, understand and quantify the dust extinction, star formation rate, metal abundance, and the two-dimensional distributions of stellar population properties of nearby galaxies. It will be important for a better understanding of galaxy formation. Here we report on the observations, data reduction, and analysis of the spectra of ~ 400 star formation regions in M33, via multifiber spectroscopy with Hectospec at the MMT.