The direct detection of annihilation products in cosmic rays offers an alternative way to search for supersymmetric dark matter particles candidates. The study of the spectrum of gamma-rays, antiprotons and positrons offers good possibilities to perform this search in a significant portion of the Minimal Supersymmetric Standard Model parameters space. In particular the EGRET team have seen a convincing signal for a strong excess of emission from the galactic center that have not easily explanation with standard processes. We will review the achievable limits with the experiment GLAST taking into accounts the LEP results and we will compare this method with the antiproton and positrons experiments, the direct underground detection and with future experiments at LHC.